منابع مشابه
Patterns of Cognitive Dysfunction in Progressive MS
BACKGROUND Progressive MS is associated with a high frequency of cognitive impairment. However, it is not clear to what extent this reflects global dysfunction, or independent deficits in specific functions. OBJECTIVE To characterise patterns of cognitive impairment in progressive MS on a multi-dimensional cognitive assessment tool well established in neurodegenerative diseases. METHODS Pat...
متن کاملLipoic acid in secondary progressive MS
Objective: To determine whether lipoic acid (LA), an endogenously produced antioxidant, slowed the whole-brain atrophy rate and was safe in secondary progressive MS (SPMS). Methods: Patients with SPMS aged 40–70 years enrolled in a single center, 2-year, double-blind, randomized trial of daily oral 1,200mg LA vs placebo. Primary outcomewas change in annualized percent change brain volume (PCBV)...
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چکیده ندارد.
15 صفحه اولP 70: Primary Progressive MS and Affecting Genes
Multiple sclerosis is a CNS autoimmune disease configured by demyelination, inflammation, and degeneration of axons. This disease inflict great harms to patients. The most common problem is inability to control musculoskeletal system and decrease in mobility. These consequences could vary from patients to patients. About 10-15% of all MS patients develop primary progressive MS (PPMS). Despite t...
متن کاملOnset of secondary progressive MS after long‐term rituximab therapy – a case report
A patient with relapsing multiple sclerosis (RMS) was treated with a standard immunomodulatory therapy, but due to ongoing disease activity was switched to rituximab. Relapses ceased, but secondary progressive MS (SPMS) eventually appeared, associated with new focal spinal cord white matter lesions. Cerebrospinal fluid (CSF) showed persistent oligoclonal bands (OCB) and clonally related B cells...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal
سال: 2017
ISSN: 1352-4585,1477-0970
DOI: 10.1177/1352458517729455